Gene description for PYCR1
Gene name pyrroline-5-carboxylate reductase 1
Gene symbol PYCR1
Other names/aliases ARCL2B
ARCL3B
P5C
P5CR
PIG45
PP222
PRO3
PYCR
Species Homo sapiens
 Experiment description of studies that identified PYCR1 in Valvular interstitial cells

1
Experiment ID1353
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 32938681   
OrganismHomo sapiens
Experiment descriptionAnnexin A1-dependent tethering promotes extracellular vesicle aggregation revealed with single-extracellular vesicle analysis
AuthorsRogers MA, Buffolo F, Schlotter F, Atkins SK, Lee LH, Halu A, Blaser MC, Tsolaki E, Higashi H, Luther K, Daaboul G, Bouten CVC, Body SC, Singh SA, Bertazzo S, Libby P, Aikawa M, Aikawa E.
Journal name Sci Adv
Publication year2020
SampleValvular interstitial cells
Sample nameAortic valve-derived primary valvular interstial cells
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK -

2
Experiment ID1354
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 32938681   
OrganismHomo sapiens
Experiment descriptionAnnexin A1-dependent tethering promotes extracellular vesicle aggregation revealed with single-extracellular vesicle analysis
AuthorsRogers MA, Buffolo F, Schlotter F, Atkins SK, Lee LH, Halu A, Blaser MC, Tsolaki E, Higashi H, Luther K, Daaboul G, Bouten CVC, Body SC, Singh SA, Bertazzo S, Libby P, Aikawa M, Aikawa E.
Journal name Sci Adv
Publication year2020
SampleValvular interstitial cells
Sample nameAortic valve-derived primary valvular interstial cells
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -

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